The virus causes birth defects in babies born to some infected pregnant women, including microcephaly, where babies are born with underdeveloped heads and brain damage. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC.The Zika virus arrived in the United States in 2016, with local transmission reported in and around Miami, FL, and Brownsville, TX.
Large-scale studies may help to understand the cause-effect relationship.ĬOVID-19 Varicella zoster herpes zoster vaccine. We could not establish definite link but there may be possible association between COVID-19 vaccine and shingles. Thirty-six patients 36/45 (80%) developed herpes zoster following the priming dose of COVID-19 vaccine among those who received mRNA vaccine. 86.27% of the cases of HZ were reported due to mRNA vaccine. Majority of the cases were from the high-income and/or middle-income countries. The mean (SD) period between development of herpes zoster and COVID-19 vaccination was 7.64 (6.92) days. There were cases with known risk factors for herpes zoster, which included age more than 50 years (n = 36), immunological disorders (n = 10), chronic disease (n = 25), metabolic disorder (n = 13), malignancy (n = 4), and psychiatric disorder (n = 2).
Individual case report references were filtered for any pertinent cases.Ī total of 54 cases consisting of 27 male and 27 female patients have been reported. We have performed a systemic review of articles from PubMed and Embase using MeSH and keywords like "Shingles," "Herpes zoster," "Varicella zoster," "COVID-19," "Vaccine," "SARS-CoV-2." No filters including country of publication, language, type of articles were applied. And to identify on whether COVID-19 vaccine has temporal relationship between development of herpes zoster (HZ). To describe the demographic, clinical, morphological characteristics, outcomes, and timing of development of herpes zoster to the various COVID-19 vaccines. Although the COVID-19 vaccination is deemed safe, exact incidence and nature if adverse effects, particularly dermatological ones, are still unknown.
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